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2023 ChABSA Annual Scientific Symposium Program
| Topic | Speaker | Organization | Abstract |
| Enabling Scientific Discovery at NIAID | Christopher Hanson | NIAID | “Enabling Scientific Discovery at NIAID” |
| Taking another look - US Biosafety Recommendations | Gigi Gronvall | Johns Hopkins Center for Health Security | |
| Assessment of environmental and occupational exposure while working with Mycobacterium abscessus in mouse models | Syadatun Ahana, MPH | HHMI Janelia Research Campus | Mycobacterium abscessus (Mabs) is a rapidly growing nontuberculous mycobacterium that is responsible for respiratory infections and other healthcare-associated extrapulmonary infections including skin and soft tissue diseases. The number of infections caused by Mabs have increased markedly in the past decade and it is hard to treat because of its resistance to standard anti-tuberculous agents, and most antimicrobial agents. As Mabs is predominantly transmitted via aerosol, using a Glas-Col aerosolizer to infect the mice would allow for a more clinically relevant model of Mabs infection. The purpose of this study was to assess if mice immunocompromised with dexamethasone and challenged with Mabs via inhalation exposure system shed Mabs bacilli orally, anally, or in their urine or on their fur, and whether using this system to create a murine model poses any occupational or environmental exposure risk. |
| Physical Hazards in Bio Laboratories | Rich Fairfax | National Safety Council | |
| Achieving Biosafety with Fewer, Safer Chemicals and Lower Costs | Eric Little Field | Trimuvirate Environmental | |
| Panel--Proactive vs. Reactive Biosafety | Megan Seltzer, Paul Meecham, Paul Landon; Dave Harbourt, moderator | Panel Discussion: Walking the line of Proactive vs.Reactive Management | |
| BREAK | |||
| Evaluation of residual quantity of Adeno-Cre in the mouse cages of individually ventilated rack after inoculation of mice with Adeno-Cre virus. | Jatinder Gulani | Laboratory Animal Science Program, The Frederick National Laboratory for Cancer Research operated by Leidos Biomedical Research, Inc. for the National Cancer Institute. | 8–10-week-old female C57BL/6 mice were inoculated with 2.5 x 107 PFU replicative defective human adenovirus serotype 5 with Cre-recombinase (Adeno-Cre) via intranasal or intratracheal route. The data demonstrates that adenoviral DNA dissipates quickly after Adeno-Cre inoculation in mice, and none is detected on the animal body and in cage environment after 10 days of inoculation. This data helped institutional biosafety committee at NCI Frederick in determining the length of ABSL-2 housing of mice (biocontainment) post Adeno-Cre virus inoculation. |
| Biosafety Customer Service: Office Hours | Jamie Pope | University of Maryland Baltimore | A major aspect of working in the field of Biosafety is that we are a service identity of the institutions we work for. But who exactly do we serve? And what do we generally do for those stakeholders? Essentially, we provide principal investigators and lab personnel with compliance services. However, open communication with PIs and their lab personnel can be difficult because of very full schedules, impending deadlines, and sporadically checking their emails. I proposed the use of Biosafety office hours; a similar approach to customer service you would typically see in academic settings. |
| Building the Relationship Between Facility Operations & Maintenance and Biosafety | Kristina M. Peterman | Merrick & Company | The operations and maintenance (O&M) staff play a key part in keeping a laboratory functioning as need to ensure biosafety and biosecurity. Often laboratory O&M staff are asked to perform preventive and corrective maintenance tasks in an unfamiliar containment environment, on complex systems and equipment. While the staff may have received general safety training as required by OSHA through an organization’s environmental health and safety program, the laboratory environment offers additional safety concerns, and there is often a disconnect between general safety and biosafety programs. We will discuss the role that biosafety has in building on an environmental health and safety program and the relationship of biorisk management with O&M staff through training, risk assessments, and ongoing communication. |
*Time and speakers subject to change.
ChABSA does not endorse speakers or verifiy contrent of presentations.